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Lipoxamycin hemisulfate
CAS No. 11075-87-9
Lipoxamycin hemisulfate ( —— )
Catalog No. M21844 CAS No. 11075-87-9
Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 329 | In Stock |
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| 5MG | 554 | In Stock |
|
| 10MG | 789 | In Stock |
|
| 25MG | 1188 | In Stock |
|
| 50MG | 1611 | In Stock |
|
| 100MG | 2151 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLipoxamycin hemisulfate
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NoteResearch use only, not for human use.
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Brief DescriptionLipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC50 of 21 nM.
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DescriptionLipoxamycin has antifungal activity against a panel of humanpathogenic fungi with better potency against some of the Candida species (MIC values, 0.25-16 μg/mL). Cryptococcus neoformans is the most sensitive organism, followed by various species of Candida. Other filamentous fungi are sensitive to the Lipoxamycin in disk diffusion assays.Lipoxamycin has a long alkyl chain and an amino-containing polar head group. Lipoxamycin is on the same order of potency as the sphingofungins and also have potent activity against the mammalianenzyme.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetFungal
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number11075-87-9
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Formula Weight421.54
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Molecular FormulaC19H36N2O5.1/2H2O4S
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Purity>98% (HPLC)
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SolubilityDMSO : 40 mg/mL (94.89 mM; ultrasonic and warming and heat to 60°C)
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SMILESOC[C@@H](C(N(O)CCC(CCCCCCC(CCCC(C)C)=O)=O)=O)N.OS(O)(=O)=O.[1/2]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. S M Mandala, et al. Inhibition of Serine Palmitoyl-Transferase Activity by Lipoxamycin. J Antibiot (Tokyo). 1994 Mar;47(3):376-9.
2. H A Whaley. The Structure of Lipoxamycin, a Novel Antifungal Antibiotic. J Am Chem Soc. 1971 Jul 28;93(15):3767-9.
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