Lipoxamycin hemisulfate

CAS No. 11075-87-9

Lipoxamycin hemisulfate( —— )

Catalog No. M21844 CAS No. 11075-87-9

Lipoxamycin has antifungal activity against a panel of humanpathogenic fungi with better potency against some of the Candida species (MIC values, 0.25-16 μg/mL).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Lipoxamycin hemisulfate
  • Note
    Research use only, not for human use.
  • Brief Description
    Lipoxamycin has antifungal activity against a panel of humanpathogenic fungi with better potency against some of the Candida species (MIC values, 0.25-16 μg/mL).
  • Description
    Lipoxamycin has antifungal activity against a panel of humanpathogenic fungi with better potency against some of the Candida species (MIC values, 0.25-16 μg/mL). Cryptococcus neoformans is the most sensitive organism, followed by various species of Candida. Other filamentous fungi are sensitive to the Lipoxamycin in disk diffusion assays.Lipoxamycin has a long alkyl chain and an amino-containing polar head group. Lipoxamycin is on the same order of potency as the sphingofungins and also have potent activity against the mammalianenzyme.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Fungal
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    11075-87-9
  • Formula Weight
    421.54
  • Molecular Formula
    C??H??N?O?.?/?H?O?S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 40 mg/mL (94.89 mM; ultrasonic and warming and heat to 60°C)
  • SMILES
    OC[C@@H](C(N(O)CCC(CCCCCCC(CCCC(C)C)=O)=O)=O)N.OS(O)(=O)=O.[1/2]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. S M Mandala, et al. Inhibition of Serine Palmitoyl-Transferase Activity by Lipoxamycin. J Antibiot (Tokyo). 1994 Mar;47(3):376-9. 2. H A Whaley. The Structure of Lipoxamycin, a Novel Antifungal Antibiotic. J Am Chem Soc. 1971 Jul 28;93(15):3767-9.
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